痛入骨髓

痛入骨髓
tòngrùgǔsuǐ
[the pain penetrates even into the marrow] 指悲痛之极、 痛心之深或怨恨之切

吾每念常痛于骨髓, 顾计不知所出耳。 --《战国策·燕策三》


Advanced Chinese dictionary. 2013.

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